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Peculiarities of rat serum proteome profile in metabolic stress.

Authors :
Sharanova NE
Vasiliev AV
Gapparov MM
Source :
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2012 Apr; Vol. 152 (6), pp. 717-9.
Publication Year :
2012

Abstract

We identified individual proteins characterizing starvation-induced metabolic stress. Sustained changes at the level of proteome caused by metabolic stress were demonstrated. Intensified synthesis of S6 kinase ribosomal protein, immunoglobulin lambda light chains, and inter-alpha-trypsin inhibitor was observed in the experimental groups.

Subjects

Subjects :
Alpha-Globulins metabolism
Animals
Electrophoresis, Gel, Two-Dimensional
Gene Expression
Gene Expression Profiling
Immunoglobulin lambda-Chains metabolism
Male
Proteome metabolism
Rats
Rats, Wistar
Ribosomal Protein S6 Kinases metabolism
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Starvation genetics
Starvation metabolism
Alpha-Globulins genetics
Immunoglobulin lambda-Chains genetics
Proteome genetics
Ribosomal Protein S6 Kinases genetics
Stress, Physiological genetics

Details

Language :
English; Russian
ISSN :
1573-8221
Volume :
152
Issue :
6
Database :
MEDLINE
Journal :
Bulletin of experimental biology and medicine
Publication Type :
Academic Journal
Accession number :
22803172
Full Text :
https://doi.org/10.1007/s10517-012-1614-y
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