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Cardiovascular drugs in pregnancy.
- Source :
-
Cardiology clinics [Cardiol Clin] 2012 Aug; Vol. 30 (3), pp. 463-91. Date of Electronic Publication: 2012 Jun 05. - Publication Year :
- 2012
-
Abstract
- Cardiovascular drugs are used in pregnancy to treat maternal and fetal conditions. Mothers may also require drug therapy postpartum. Most cardiovascular drugs taken by pregnant women can cross the placenta and therefore expose the developing embryo and fetus to their pharmacologic and teratogenic effects. These effects are influenced by the intrinsic pharmacokinetic properties of a given drug and by the complex physiologic changes occurring during pregnancy. Many drugs are also transferred into human milk with potential adverse effects on the nursing infant. This article summarizes some of the literature concerning the risks and benefits of using cardiovascular drugs during pregnancy.<br /> (Copyright © 2012 Elsevier Inc. All rights reserved.)
- Subjects :
- Abnormalities, Drug-Induced etiology
Anti-Arrhythmia Agents pharmacokinetics
Anti-Arrhythmia Agents therapeutic use
Anticholesteremic Agents pharmacokinetics
Anticholesteremic Agents therapeutic use
Anticoagulants pharmacokinetics
Anticoagulants therapeutic use
Arrhythmias, Cardiac drug therapy
Cardiac Glycosides pharmacokinetics
Cardiac Glycosides therapeutic use
Cardiovascular Agents pharmacokinetics
Female
Fibrinolytic Agents therapeutic use
Humans
Hypertension, Pregnancy-Induced drug therapy
Maternal-Fetal Exchange physiology
Platelet Aggregation Inhibitors pharmacokinetics
Platelet Aggregation Inhibitors therapeutic use
Pregnancy
Cardiovascular Agents therapeutic use
Pregnancy Complications, Cardiovascular drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1558-2264
- Volume :
- 30
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Cardiology clinics
- Publication Type :
- Academic Journal
- Accession number :
- 22813371
- Full Text :
- https://doi.org/10.1016/j.ccl.2012.04.007