Back to Search
Start Over
Epidemiological and microbiological profile of infective keratitis in Ahmedabad.
- Source :
-
Indian journal of ophthalmology [Indian J Ophthalmol] 2012 Jul; Vol. 60 (4), pp. 267-72. - Publication Year :
- 2012
-
Abstract
- Context: Study of patients attending tertiary care ophthalmology institute at Ahmedabad.<br />Aims: To study the microbiological etiology and epidemiological factors associated with suppurative keratitis.<br />Settings and Design: A total of 150 corneal scrapings were evaluated from patients presenting with corneal ulcers at a tertiary ophthalmology center, Ahmedabad from July 2007 to June 2008.<br />Materials and Methods: Scrapings were subjected to Gram stain, potassium hydroxide preparation and culture for bacterial and fungal pathogens. Socio-demographic data and risk factors were recorded.<br />Results: Ninety percent (135/150) people with corneal ulcers had trauma as predisposing factor for keratitis. Trauma due to wooden objects was the leading cause (46/135) followed by vegetable matter and stone injury (23/135). Microbial etiology was established in 59.3% (89/150) of scrapings. Out of 89 positive isolates, 65.1% (58/89) were bacterial while 34.9% (31/89) were fungal. Among the bacterial isolates, 60.3% (35/58) were Gram-positive cocci while 39.7% (23/58) were Gram-negative bacilli. The most common bacterial isolate was Staphylococus aureus (32.7%, 19/58) followed by coagulase-negative Staphylococci (25.8%, 15/58) and Pseudomonas (18.9%, 11/58). Among the 31 fungal pathogens, Aspergillus species was the most common (35.4%11/31), followed by Fusarium species (22.5%, 7/31).<br />Conclusion: Trauma with wooden material is the most common predisposing factor for suppurative keratitis. Males were more affected than females. Bacterial ulcers were more common than fungal in areas in and around Ahmedabad. Staphylococcus aureus and Aspergillus were the commonest bacterial and fungal isolates respectively. Geographical variation persists in microbial etiology of suppurative keratitis.
- Subjects :
- Adult
Age Distribution
Cornea pathology
Eye Infections, Bacterial microbiology
Eye Infections, Fungal microbiology
Female
Humans
Incidence
India epidemiology
Keratitis microbiology
Male
Microscopy, Acoustic
Middle Aged
Retrospective Studies
Young Adult
Bacteria isolation & purification
Cornea microbiology
Eye Infections, Bacterial epidemiology
Eye Infections, Fungal epidemiology
Fungi isolation & purification
Keratitis epidemiology
Urban Population
Subjects
Details
- Language :
- English
- ISSN :
- 1998-3689
- Volume :
- 60
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Indian journal of ophthalmology
- Publication Type :
- Academic Journal
- Accession number :
- 22824594
- Full Text :
- https://doi.org/10.4103/0301-4738.98702