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Psychometric properties of the 8-item Morisky Medication Adherence Scale in patients taking warfarin.
- Source :
-
Thrombosis and haemostasis [Thromb Haemost] 2012 Oct; Vol. 108 (4), pp. 789-95. Date of Electronic Publication: 2012 Jul 26. - Publication Year :
- 2012
-
Abstract
- There is no patient-reported medication adherence measure that has been validated in Singapore. This study aimed to validate the 8-item Morisky Medication Adherence Scale (MMAS) in patients taking warfarin in Singapore. A cross-sectional survey was conducted in a convenience sample of 151 patients taking warfarin at an anticoagulation clinic in 2011. Respondents completed the MMAS in English or Chinese depending on their preference. The MMAS had a Cronbach's alpha of 0.56 and good criterion-related validity as the scale scores were associated with warfarin refill rates (p = 0.04). Respondents with higher MMAS scores were found to have a higher percentage of International Normalised Ratios (INRs) within the therapeutic range (p = 0.01), higher adherence to diet recommendations (p = 0.02), and less perceived difficulty in taking all medications (p < 0.001); they were also more likely to take warfarin at the same time every day (p < 0.001). Confirmatory factor analysis showed that the eight items loaded onto one factor (RMSEA = 0.03). The sensitivity, specificity, positive predictive value and negative predictive value of the MMAS for identifying patients with poor INR control were 73.0%, 35.6%, 49.5% and 60.5%, respectively, using the time in the therapeutic INR range as the gold standard. This study shows that the 8-item MMAS has good validity and moderate reliability in patients taking warfarin. Future research is needed to investigate the scale's psychometric properties in other patient populations and clinical settings.
- Subjects :
- Adult
Aged
Anticoagulants administration & dosage
Cross-Sectional Studies
Female
Humans
International Normalized Ratio
Language
Male
Middle Aged
Psychometrics
Reproducibility of Results
Singapore
Surveys and Questionnaires
Medication Adherence psychology
Medication Adherence statistics & numerical data
Warfarin administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 2567-689X
- Volume :
- 108
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Thrombosis and haemostasis
- Publication Type :
- Academic Journal
- Accession number :
- 22836920
- Full Text :
- https://doi.org/10.1160/TH12-05-0368