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Population versus customized fetal growth norms and adverse outcomes in an intrapartum cohort.

Authors :
Costantine MM
Lai Y
Bloom SL
Spong CY
Varner MW
Rouse DJ
Ramin SM
Caritis SN
Peaceman AM
Sorokin Y
Sciscione A
Mercer BM
Thorp JM
Malone FD
Harper M
Iams JD
Source :
American journal of perinatology [Am J Perinatol] 2013 Apr; Vol. 30 (4), pp. 335-41. Date of Electronic Publication: 2012 Aug 14.
Publication Year :
2013

Abstract

Objective: To compare population versus customized fetal growth norms in identifying neonates at risk for adverse outcomes (APO) associated with small for gestational age (SGA).<br />Study Design: Secondary analysis of an intrapartum fetal pulse oximetry trial in nulliparous women at term. Birth weight percentiles were calculated using ethnicity- and gender-specific population norms and customized norms (Gardosi).<br />Results: Of the studied neonates, 508 (9.9%) and 584 (11.3%) were SGA by population (SGApop) and customized (SGAcust) norms, respectively. SGApop infants were significantly associated with a composite adverse neonatal outcome, neonatal intensive care admission, low fetal oxygen saturation, and reduced risk of cesarean delivery; both SGApop and SGAcust infants were associated with a 5-minute Apgar score < 4. The ability of customized and population birth weight percentiles in predicting APO was poor (12 of 14 APOs had area under the curve of <0.6).<br />Conclusion: In this intrapartum cohort, neither customized nor normalized population norms adequately identified neonates at risk of APO related to SGA.<br /> (Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.)

Details

Language :
English
ISSN :
1098-8785
Volume :
30
Issue :
4
Database :
MEDLINE
Journal :
American journal of perinatology
Publication Type :
Academic Journal
Accession number :
22893556
Full Text :
https://doi.org/10.1055/s-0032-1324708