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Frequency of excisions and yields of malignant skin tumors in a population-based screening intervention of 360,288 whole-body examinations.
- Source :
-
Archives of dermatology [Arch Dermatol] 2012 Aug; Vol. 148 (8), pp. 903-10. - Publication Year :
- 2012
-
Abstract
- Objective: To explore the frequency of excisions and yields of histopathologically confirmed skin cancer.<br />Design: A population-based skin cancer screening intervention (the SCREEN project) in the German state of Schleswig-Holstein (July 1, 2003, to June 30, 2004).<br />Setting: Physician offices. Participants could choose between nondermatologist physicians and dermatologists for their initial whole-body skin examination. All screening physicians received a mandatory 8-hour training course. PARTICIPANTS Inhabitants of Schleswig-Holstein 20 years or older with statutory health insurance (N = 360,288).<br />Main Outcome Measures: Frequency of excisions and yields of malignant skin tumors (malignant melanomas [MMs], basal cell carcinomas [BCCs], and squamous cell carcinomas [SCCs]), stratified by sex and age.<br />Results: Overall, 15,983 excisions were performed (1 of 23 screenees). A total of 3103 malignant skin tumors were diagnosed in 2911 persons: 585 MMs, 1961 BCCs, 392 SCCs, and 165 other malignant skin tumors. Overall, 116 persons (3103 of 360,288) had to be screened to find 1 malignant tumor, with 1 of 620 for MM, 1 of 184 for BCC, and 1 of 920 for SCC. Twenty excisions were performed to find 1 melanoma in men 65 years and older, but more than 50 excisions were required to find 1 melanoma in men aged between 20 and 49 years.<br />Conclusions: The results of SCREEN suggest a high yield of malignant skin tumors in a large-scale population-based screening project. We found that a high number of excisions was performed in the youngest screenees with an associated low yield, suggesting a need in screener training to emphasize a more conservative attitude toward excisions in young screenees.
- Subjects :
- Adult
Aged
Carcinoma, Basal Cell diagnosis
Carcinoma, Basal Cell epidemiology
Carcinoma, Squamous Cell diagnosis
Carcinoma, Squamous Cell epidemiology
Early Detection of Cancer statistics & numerical data
Female
Germany epidemiology
Humans
Male
Melanoma diagnosis
Melanoma epidemiology
Middle Aged
Skin Neoplasms diagnosis
Young Adult
Carcinoma, Basal Cell surgery
Carcinoma, Squamous Cell surgery
Mass Screening statistics & numerical data
Melanoma surgery
Skin Neoplasms epidemiology
Skin Neoplasms surgery
Subjects
Details
- Language :
- English
- ISSN :
- 1538-3652
- Volume :
- 148
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Archives of dermatology
- Publication Type :
- Academic Journal
- Accession number :
- 22911184
- Full Text :
- https://doi.org/10.1001/archdermatol.2012.893