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Comparison of different positron emission tomography tracers in patients with recurrent medullary thyroid carcinoma: our experience and a review of the literature.
- Source :
-
Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer [Recent Results Cancer Res] 2013; Vol. 194, pp. 385-93. - Publication Year :
- 2013
-
Abstract
- Several morphological and functional imaging techniques are usually used to detect residual/recurrent medullary thyroid carcinoma (MTC) with variable results; currently, there is growing interest in positron emission tomography (PET) methodology. Herein, we report our experience of and a literature review about the comparison of different positron emission tomography (PET) tracers in patients with residual/recurrent MTC. (18)F-DOPA PET/CT seems to be the most useful imaging method to detect recurrent MTC lesions, performing better than (18)F-FDG and (68)Ga-somatostatin analogs PET/CT. (18)F-FDG may complement (18)F-DOPA in patients with aggressive tumors. (68)Ga-somatostatin analogs PET/CT may be useful to select patients who could benefit from radioreceptor therapy. The information provided by the various PET tracers reflects different metabolic pathways, and may help to select the most appropriate treatment.
- Subjects :
- Adult
Aged
Aged, 80 and over
Carcinoma, Neuroendocrine
Dihydroxyphenylalanine analogs & derivatives
Female
Fluorodeoxyglucose F18
Humans
Male
Middle Aged
Multimodal Imaging methods
Neoplasm Recurrence, Local diagnostic imaging
Positron-Emission Tomography
Radiopharmaceuticals
Thyroid Neoplasms diagnostic imaging
Tomography, X-Ray Computed
Subjects
Details
- Language :
- English
- ISSN :
- 0080-0015
- Volume :
- 194
- Database :
- MEDLINE
- Journal :
- Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer
- Publication Type :
- Academic Journal
- Accession number :
- 22918771
- Full Text :
- https://doi.org/10.1007/978-3-642-27994-2_21