Back to Search
Start Over
Down's syndrome and Alzheimer's disease: towards secondary prevention.
- Source :
-
Nature reviews. Drug discovery [Nat Rev Drug Discov] 2012 Sep; Vol. 11 (9), pp. 655-6. - Publication Year :
- 2012
-
Abstract
- A public-private partnership to establish biomarkers of dementia in Down's syndrome could aid the development of preventive therapies for the dementia associated with both Down's syndrome and Alzheimer's disease, based on the apparent common pathogenic role of amyloid precursor protein in the two conditions.
- Subjects :
- Alzheimer Disease etiology
Alzheimer Disease genetics
Amyloid beta-Peptides adverse effects
Amyloid beta-Peptides genetics
Apolipoprotein E4 adverse effects
Apolipoprotein E4 genetics
Down Syndrome etiology
Down Syndrome genetics
Genetic Markers genetics
Genotype
Humans
Alzheimer Disease prevention & control
Down Syndrome prevention & control
Secondary Prevention methods
Subjects
Details
- Language :
- English
- ISSN :
- 1474-1784
- Volume :
- 11
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Nature reviews. Drug discovery
- Publication Type :
- Academic Journal
- Accession number :
- 22935789
- Full Text :
- https://doi.org/10.1038/nrd3822