Apoptosis as a mechanism of maxillary sinus mucosa injury in rats after experimental transection of the maxillary nerve.

Authors :: Edranov SS
Motavkin PA
Source :: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2012 Aug; Vol. 153 (4), pp. 526-9.
Publication Year :: 2012
Abstract: Transection of the maxillary nerve initiates apoptosis of the maxillary sinus mucosa cells in rats. Significant activation of apoptosis and proapoptotic factor p53 was found in the epithelium during week 1 after nerve transection. In delayed period after injury, apoptotic cells predominated in the submucosa against the background of Bcl-2 hypoexpression.

Subjects :: Animals
Immunohistochemistry
In Situ Nick-End Labeling
Maxillary Nerve injuries
Maxillary Sinus injuries
Proto-Oncogene Proteins c-bcl-2 metabolism
Rats
Tumor Suppressor Protein p53 metabolism
Apoptosis physiology
Maxillary Nerve physiopathology
Maxillary Sinus cytology
Nasal Mucosa injuries
Trigeminal Nerve Injuries physiopathology

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