Failure of surgery and isotretinoin to relieve jaw immobilization in fibrodysplasia ossificans progressiva: report of two cases.

Authors :: Crofford LJ
Brahim JS
Zasloff MA
Marini JC
Source :: Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons [J Oral Maxillofac Surg] 1990 Feb; Vol. 48 (2), pp. 204-8.
Publication Year :: 1990
Abstract: Two patients with fibrodysplasia ossificans progressiva who presented with jaw immobilization due to formation of bone between the maxilla and mandible were treated with surgical resection of their ectopic bone in conjunction with experimental, adjunctive medical therapy using isotretinoin. Both patients had recurrence of their ectopic ossification within 2 months of surgery. Surgery to remove joint-bridging ossifications in FOP is not recommended.

Subjects :: Adolescent
Child, Preschool
Humans
Jaw Diseases drug therapy
Male
Myositis Ossificans drug therapy
Recurrence
Isotretinoin therapeutic use
Jaw Diseases surgery
Myositis Ossificans surgery

Language :: English
ISSN :: 0278-2391
Volume :: 48
Issue :: 2
Database :: MEDLINE
Journal :: Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
Publication Type :: Academic Journal
Accession number :: 2299462
Full Text :: https://doi.org/10.1016/s0278-2391(10)80212-5

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