Immobilization of liposomes and vesicles on patterned surfaces by a peptide coiled-coil binding motif.

Authors :: Voskuhl J
Wendeln C
Versluis F
Fritz EC
Roling O
Zope H
Schulz C
Rinnen S
Arlinghaus HF
Ravoo BJ
Kros A
Source :: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2012 Dec 07; Vol. 51 (50), pp. 12616-20. Date of Electronic Publication: 2012 Sep 26.
Publication Year :: 2012
Abstract: Patchy surfaces: An azide-terminated self-assembled monolayer was patterned with the peptide sequence (EIAALEK)(3) by using microcontact printing. This sequence forms stable coiled-coil heterodimers with the complementary peptide (KIAALKE)(3). By introducing this peptide to the surface of phospholipid liposomes and cyclodextrin vesicles, liposomes and vesicles can be immobilized at the patterned surface.<br /> (Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Subjects :: Amino Acid Sequence
Click Chemistry
Dimethylpolysiloxanes chemistry
Protein Binding
Surface Properties
Liposomes chemistry
Peptides chemistry

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