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[The role of markers of inflammation in assessment of prognosis in patients with ST-elevation myocardial infarction combined with disturbances of carbohydrate metabolism].
- Source :
-
Kardiologiia [Kardiologiia] 2012; Vol. 52 (8), pp. 20-6. - Publication Year :
- 2012
-
Abstract
- Diabetes mellitus (DM) is not only an independent risk factor (RF) of development of atherosclerosis, but it substantially worsens prognosis of patients with acute myocardial infarction (MI). Results of this study evidence that presence of disturbances of carbohydrate metabolism (DM or impaired glucose tolerance (IGT) in patients with ST elevation MI manifests with higher activity of the inflammatory process compared with patients with MI without abnormalities of carbohydrate metabolism. Unfavorable 1 year prognosis in patients with ST elevation MI is associated with higher concentrations of inflammation markers assessed on days 10-14 from onset of the disease: in patients with DM and IGT- of sCD40 ligand, in patients without disturbances of carbohydrate metabolism - C-reactive protein, in all patients irrespective of presence of carbohydrate metabolism abnormalities - interleukin 12.
- Subjects :
- Aged
Biomarkers blood
Blood Glucose metabolism
C-Reactive Protein metabolism
Disease Progression
Female
Follow-Up Studies
Humans
Male
Middle Aged
Myocardial Infarction diagnosis
Myocardial Infarction mortality
Prognosis
Siberia epidemiology
Survival Rate trends
Time Factors
Carbohydrates blood
Electrocardiography
Inflammation blood
Myocardial Infarction blood
Risk Assessment methods
Subjects
Details
- Language :
- Russian
- ISSN :
- 0022-9040
- Volume :
- 52
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Kardiologiia
- Publication Type :
- Academic Journal
- Accession number :
- 23098394