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Association of constitutional type of Ayurveda with cardiovascular risk factors, inflammatory markers and insulin resistance.
- Source :
-
Journal of Ayurveda and integrative medicine [J Ayurveda Integr Med] 2012 Jul; Vol. 3 (3), pp. 150-7. - Publication Year :
- 2012
-
Abstract
- Context: Ayurveda propounds that diseases manifest from imbalance of doshas. There, have been attempts to indicate biochemical basis of constitutional types described in Ayurveda.<br />Aims: The study was intended to assess the association of constitutional types (Prakriti) with cardiovascular risk factors, inflammatory markers and insulin resistance in subjects with coronary artery disease (CAD).<br />Settings and Design: Hospital based cross sectional study.<br />Materials and Methods: Three hundred patients with CAD >25 years were studied. Assessment of Prakriti was done by using Ayusoft software. Biochemical parameters, inflammatory markers (hsCRP, TNF-alpha and IL-6) and insulin resistance (HOMA-IR) were measured.<br />Statistical Analysis: Was done using EPI INFO, version 3.5.3.<br />Results: Mean age of patients was 60.97±12.5 years. Triglyceride, VLDL and LDL was significantly higher (P<0.0001, P<0.0001 and 0.0355, respectively) and HDL cholesterol (P<0.0001) significantly lower in vatta kapha (VK) Prakriti when compared with other constitution type. VK Prakriti was correlated with diabetes mellitus (r=0.169, P=0.003), hypertension (r=0.211, P≤0.0001) and dyslipidemia (r=0.541, P≤0.0001). Inflammatory markers; IL6, TNF alpha, hsCRP and HOMA IR was highest in VK Prakriti. Inflammatory markers were correlated positively with both VK and Kapha group.<br />Conclusions: There is strong relation of risk factors (diabetes, hypertension, dyslipidemia), insulin resistance, and inflammatory markers with Vata Kapha and Kapha Prakriti.
Details
- Language :
- English
- ISSN :
- 0976-2809
- Volume :
- 3
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of Ayurveda and integrative medicine
- Publication Type :
- Academic Journal
- Accession number :
- 23125512
- Full Text :
- https://doi.org/10.4103/0975-9476.100186