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Identity crisis: it's not just Foxp3 anymore.

Authors :
Delgoffe GM
Bettini ML
Vignali DA
Source :
Immunity [Immunity] 2012 Nov 16; Vol. 37 (5), pp. 759-61.
Publication Year :
2012

Abstract

What does it take to make a regulatory T (Treg) cell? In this issue of Immunity, Ohkura et al. show that Treg-cell-specific CpG hypomethylation and Foxp3 expression are independent events required for Treg cell development, stability, and full suppressive activity.<br /> (Copyright © 2012 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1097-4180
Volume :
37
Issue :
5
Database :
MEDLINE
Journal :
Immunity
Publication Type :
Academic Journal
Accession number :
23159220
Full Text :
https://doi.org/10.1016/j.immuni.2012.10.012