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Performance of Eudragit coated whispering gallery mode resonator-based immunosensors.

Authors :
Giannetti A
Berneschi S
Baldini F
Cosi F
Conti GN
Soria S
Source :
Sensors (Basel, Switzerland) [Sensors (Basel)] 2012 Oct 30; Vol. 12 (11), pp. 14604-11. Date of Electronic Publication: 2012 Oct 30.
Publication Year :
2012

Abstract

Whispering gallery mode resonators (WGMR) are an efficient tool for the realization of optical biosensors. A high Q factor preservation is a crucial requirement for good biosensor performances. In this work we present an Eudragit®L100 coated microspherical WGMR as an efficient immunosensor. The developed resonator was morphologically characterized using fluorescence microscopy. The functionalization process was tuned to preserve the high Q factor of the resonator. The protein binding assay was optically characterized in terms of specificity in buffer solution.

Details

Language :
English
ISSN :
1424-8220
Volume :
12
Issue :
11
Database :
MEDLINE
Journal :
Sensors (Basel, Switzerland)
Publication Type :
Academic Journal
Accession number :
23202178
Full Text :
https://doi.org/10.3390/s121114604