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Plasmodium vivax malaria in Mali: a study from three different regions.
- Source :
-
Malaria journal [Malar J] 2012 Dec 05; Vol. 11, pp. 405. Date of Electronic Publication: 2012 Dec 05. - Publication Year :
- 2012
-
Abstract
- Background: Plasmodium vivax has traditionally been considered virtually absent from Western and Central Africa, due to the absence of the Duffy blood group in most of the population living in these areas. Recent reports, however, suggest the circulation of P. vivax in sub-Saharan Africa.<br />Methods: Giemsa/Field-stained smears from febrile patients recruited in five different cities (Goundam, Tombouctou, Gao, Bourem and Kidal) pertaining to three regions from Northern Mali were examined. Nested-PCR and DNA sequence analyses of selected samples were performed to fully confirm the presence of P. vivax infections.<br />Results: Results demonstrated the presence of P. vivax infections in close to 30% of the cases as detected by Giemsa/Field-stained smears and nested-PCR and DNA-sequence analyses of selected samples unequivocally confirmed the presence of P. vivax.<br />Conclusions: The diagnostics of this human malaria parasite should be taken into account in the context of malaria control and elimination efforts, not only in Mali, but also in sub-Saharan Africa.
- Subjects :
- DNA, Protozoan blood
DNA, Protozoan genetics
Duffy Blood-Group System
Humans
Malaria, Vivax diagnosis
Malaria, Vivax parasitology
Mali epidemiology
Molecular Epidemiology
Phylogeny
Plasmodium vivax classification
Plasmodium vivax genetics
Plasmodium vivax isolation & purification
Polymerase Chain Reaction
RNA, Protozoan genetics
Malaria, Vivax epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1475-2875
- Volume :
- 11
- Database :
- MEDLINE
- Journal :
- Malaria journal
- Publication Type :
- Academic Journal
- Accession number :
- 23217064
- Full Text :
- https://doi.org/10.1186/1475-2875-11-405