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Cerebral amyloid angiopathy--an underdiagnosed entity in younger adults with lobar intracerebral hemorrhage?
- Source :
-
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis [Amyloid] 2013 Mar; Vol. 20 (1), pp. 45-7. Date of Electronic Publication: 2012 Dec 12. - Publication Year :
- 2013
-
Abstract
- Cerebral amyloid angiopathy (CAA) is a progressive microvascular amyloidosis affecting the small- and medium-sized arterioles and the capillaries of brain parenchyma and leptomeninges, and is recognized as a cause of lobar intracerebral hemorrhage (ICH). We report two patients who experienced recurrent ICH due to CAA at an age of 37 (A) and 42 (B) years, respectively. The classic and modified Boston criteria for the diagnosis of CAA include an age limit of 55 years if no biopsy or postmortem examination is performed; CAA is typically not considered in the differential diagnosis of lobar ICH in younger patients. We assume that sporadic CAA is an underdiagnosed entity in younger adults with lobar ICH.
- Subjects :
- Adult
Brain diagnostic imaging
Cerebral Amyloid Angiopathy complications
Cerebral Amyloid Angiopathy diagnostic imaging
Cerebral Amyloid Angiopathy pathology
Cerebral Hemorrhage complications
Cerebral Hemorrhage diagnostic imaging
Cerebral Hemorrhage pathology
Humans
Male
Radiography
Brain pathology
Cerebral Amyloid Angiopathy diagnosis
Cerebral Hemorrhage diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1744-2818
- Volume :
- 20
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis
- Publication Type :
- Academic Journal
- Accession number :
- 23231422
- Full Text :
- https://doi.org/10.3109/13506129.2012.746937