Isolated vertebral metastasis with a fluid-fluid level from a poorly differentiated adenocarcinoma.

Fluid-fluid level in bone metastases is an extremely rare finding, with only five case reports published in the literature. Here we report a case of an atypical isolated bone metastasis presenting with a fluid-fluid level revealing lung cancer in a 47-year-old patient without history of cancer. The differential diagnosis and imaging features are discussed with reference to the relevant literature.