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[Children with obesity and declining linear growth curve: Cushing's disease?].

Authors :
van Wezel EM
van Santen HM
van Furth W
Reneman L
Bisschop PH
van Trotsenburg AS
Source :
Nederlands tijdschrift voor geneeskunde [Ned Tijdschr Geneeskd] 2012; Vol. 156 (51), pp. A4677.
Publication Year :
2012

Abstract

We describe two children who presented with extreme weight gain and failure to grow in height, and who were both diagnosed with Cushing's disease. Following preoperative metyrapone treatment, both children successfully underwent curative transsphenoidal surgery. While obesity is a common and increasing problem in childhood, Cushing's disease is rare. The combination of weight gain and growth failure in a child is an alarming sign in which underlying endocrine disease must be ruled out.

Details

Language :
Dutch; Flemish
ISSN :
1876-8784
Volume :
156
Issue :
51
Database :
MEDLINE
Journal :
Nederlands tijdschrift voor geneeskunde
Publication Type :
Academic Journal
Accession number :
23249505