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Reactions of difluorocarbene with organozinc reagents.

Authors :
Levin VV
Zemtsov AA
Struchkova MI
Dilman AD
Source :
Organic letters [Org Lett] 2013 Feb 15; Vol. 15 (4), pp. 917-9. Date of Electronic Publication: 2013 Jan 31.
Publication Year :
2013

Abstract

Reactions of difluorocarbene with benzyl and alkylzinc halides leading to fluorinated organozinc species have been described. The generated α-difluorinated organozinc reagents are reasonably stable in solution and can be quenched with external electrophiles (iodine, bromine, proton), affording compounds containing the CF(2) fragment.

Details

Language :
English
ISSN :
1523-7052
Volume :
15
Issue :
4
Database :
MEDLINE
Journal :
Organic letters
Publication Type :
Academic Journal
Accession number :
23368906
Full Text :
https://doi.org/10.1021/ol400122k