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[Chemotherapy for small cell lung cancer with brain metastases].
- Source :
-
Bulletin du cancer [Bull Cancer] 2013 Jan 01; Vol. 100 (1), pp. 89-93. - Publication Year :
- 2013
-
Abstract
- Patients with small cell lung cancer present initially with brain metastases in 10 to 24 % of the cases when detected respectively by CT scan or Gadolinium-enhanced MRI of the brain. The aim of this review is to evaluate the effectiveness of systemic chemotherapy for the treatment of brain metastases from small cell lung cancer in first and second line: in fact, there are only case reports, small phase II studies and one phase III study. In spite of the scarcity of these data, the efficacy of the systemic treatment is shown and the guidelines recommend the use of chemotherapy, particularly in asymptomatic patients.
- Subjects :
- Asymptomatic Diseases therapy
Clinical Trials, Phase II as Topic
Clinical Trials, Phase IV as Topic
Humans
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Brain Neoplasms drug therapy
Brain Neoplasms secondary
Lung Neoplasms
Small Cell Lung Carcinoma drug therapy
Small Cell Lung Carcinoma secondary
Subjects
Details
- Language :
- French
- ISSN :
- 1769-6917
- Volume :
- 100
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Bulletin du cancer
- Publication Type :
- Academic Journal
- Accession number :
- 23392751
- Full Text :
- https://doi.org/10.1684/bdc.2012.1687