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Electrolyte imbalances and nephrocalcinosis in acute phosphate poisoning on chronic type 1 renal tubular acidosis due to Sjögren's syndrome.
- Source :
-
Journal of Korean medical science [J Korean Med Sci] 2013 Feb; Vol. 28 (2), pp. 336-9. Date of Electronic Publication: 2013 Jan 29. - Publication Year :
- 2013
-
Abstract
- Although renal calcium crystal deposits (nephrocalcinosis) may occur in acute phosphate poisoning as well as type 1 renal tubular acidosis (RTA), hyperphosphatemic hypocalcemia is common in the former while normocalcemic hypokalemia is typical in the latter. Here, as a unique coexistence of these two seperated clinical entities, we report a 30-yr-old woman presenting with carpal spasm related to hypocalcemia (ionized calcium of 1.90 mM/L) due to acute phosphate poisoning after oral sodium phosphate bowel preparation, which resolved rapidly after calcium gluconate intravenously. Subsequently, type 1 RTA due to Sjögren's syndrome was unveiled by sustained hypokalemia (3.3 to 3.4 mEq/L), persistent alkaline urine pH (> 6.0) despite metabolic acidosis, and medullary nephrocalcinosis. Through this case report, the differential points of nephrocalcinosis and electrolyte imbalances between them are discussed, and focused more on diagnostic tests and managements of type 1 RTA.
- Subjects :
- Acidosis, Renal Tubular etiology
Acute Disease
Adult
Antibodies, Antinuclear blood
Calcium Gluconate therapeutic use
Chronic Disease
Female
Humans
Hydrogen-Ion Concentration
Hypocalcemia complications
Hypocalcemia drug therapy
Nephrocalcinosis complications
Nephrocalcinosis diagnostic imaging
Parotid Gland diagnostic imaging
Radionuclide Imaging
Salivary Glands diagnostic imaging
Sjogren's Syndrome complications
Sjogren's Syndrome metabolism
Submandibular Gland diagnostic imaging
Ultrasonography
Acidosis, Renal Tubular diagnosis
Hypocalcemia chemically induced
Nephrocalcinosis diagnosis
Phosphates adverse effects
Sjogren's Syndrome diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1598-6357
- Volume :
- 28
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Journal of Korean medical science
- Publication Type :
- Academic Journal
- Accession number :
- 23400265
- Full Text :
- https://doi.org/10.3346/jkms.2013.28.2.336