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Serum fetuin-A levels are associated with the presence and severity of coronary artery disease in patients with type 2 diabetes.

Authors :
Zhao ZW
Lin CG
Wu LZ
Luo YK
Fan L
Dong XF
Zheng H
Source :
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals [Biomarkers] 2013 Mar; Vol. 18 (2), pp. 160-4.
Publication Year :
2013

Abstract

Objective: To clarify the correlation between serum fetuin-A levels and the presence and severity of coronary artery disease (CAD) in patients with type 2 diabetes (T2DM).<br />Methods: A total of 241 consecutive patients with T2DM and 69 controls were recruited. Serum fetuin-A levels were analyzed by enzyme-linked immunosorbent assay. The presence and severity of CAD were evaluated by coronary angiography (CAG).<br />Results: Serum fetuin-A levels are independently correlated with the presence and severity of CAD in T2DM patients.<br />Conclusions: Fetuin-A might serve as a potential biomarker for reflecting the development and progression of CAD in T2DM patients.

Details

Language :
English
ISSN :
1366-5804
Volume :
18
Issue :
2
Database :
MEDLINE
Journal :
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals
Publication Type :
Academic Journal
Accession number :
23410047
Full Text :
https://doi.org/10.3109/1354750X.2012.762806