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Serum fetuin-A levels are associated with the presence and severity of coronary artery disease in patients with type 2 diabetes.
- Source :
-
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals [Biomarkers] 2013 Mar; Vol. 18 (2), pp. 160-4. - Publication Year :
- 2013
-
Abstract
- Objective: To clarify the correlation between serum fetuin-A levels and the presence and severity of coronary artery disease (CAD) in patients with type 2 diabetes (T2DM).<br />Methods: A total of 241 consecutive patients with T2DM and 69 controls were recruited. Serum fetuin-A levels were analyzed by enzyme-linked immunosorbent assay. The presence and severity of CAD were evaluated by coronary angiography (CAG).<br />Results: Serum fetuin-A levels are independently correlated with the presence and severity of CAD in T2DM patients.<br />Conclusions: Fetuin-A might serve as a potential biomarker for reflecting the development and progression of CAD in T2DM patients.
- Subjects :
- Aged
Biomarkers blood
Blood Pressure
Body Mass Index
Case-Control Studies
Coronary Artery Disease complications
Coronary Artery Disease diagnostic imaging
Coronary Artery Disease pathology
Coronary Vessels diagnostic imaging
Coronary Vessels pathology
Diabetes Mellitus, Type 2 complications
Diabetes Mellitus, Type 2 diagnostic imaging
Diabetes Mellitus, Type 2 pathology
Female
Humans
Lipoproteins, LDL blood
Male
Middle Aged
Radiography
Severity of Illness Index
Triglycerides blood
alpha-2-HS-Glycoprotein analysis
Coronary Artery Disease blood
Coronary Vessels metabolism
Diabetes Mellitus, Type 2 blood
alpha-2-HS-Glycoprotein metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 1366-5804
- Volume :
- 18
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals
- Publication Type :
- Academic Journal
- Accession number :
- 23410047
- Full Text :
- https://doi.org/10.3109/1354750X.2012.762806