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Chest wall shrapnel-induced beryllium-sensitization and associated pulmonary disease.
- Source :
-
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG [Sarcoidosis Vasc Diffuse Lung Dis] 2012 Oct; Vol. 29 (2), pp. 147-50. - Publication Year :
- 2012
-
Abstract
- Chronic beryllium disease (CBD) is an exposure-related granulomatous disease mimicking sarcoidosis. Beryllium exposure-associated disease occurs mainly via inhalation, but skin may also be a source of sensitization. A 65-year-old male with a history of war-related shrapnel wounds was initially diagnosed with pulmonary sarcoidosis. Twenty years later, the possibility of a metal-related etiology for the lung disease was raised. A beryllium lymphocyte proliferation test, elemental analysis of removed shrapnel, and genetic studies were consistent with a diagnosis of CBD. This case demonstrates that retained beryllium-containing foreign bodies can be linked to a pathophysiologic response in the lung consistent with CBD.
Details
- Language :
- English
- ISSN :
- 1124-0490
- Volume :
- 29
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG
- Publication Type :
- Academic Journal
- Accession number :
- 23461078