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A powerful molecular synergy between mutant Nucleophosmin and Flt3-ITD drives acute myeloid leukemia in mice.
- Source :
-
Leukemia [Leukemia] 2013 Sep; Vol. 27 (9), pp. 1917-20. Date of Electronic Publication: 2013 Mar 12. - Publication Year :
- 2013
- Subjects :
- Animals
Cell Transformation, Neoplastic genetics
Disease Models, Animal
Leukemia, Myeloid, Acute metabolism
Mice
Mice, Knockout
Nuclear Proteins metabolism
Nucleophosmin
fms-Like Tyrosine Kinase 3 metabolism
Epistasis, Genetic
Leukemia, Myeloid, Acute genetics
Mutation
Nuclear Proteins genetics
Tandem Repeat Sequences
fms-Like Tyrosine Kinase 3 genetics
Subjects
Details
- Language :
- English
- ISSN :
- 1476-5551
- Volume :
- 27
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Leukemia
- Publication Type :
- Report
- Accession number :
- 23478666
- Full Text :
- https://doi.org/10.1038/leu.2013.77