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[Brachytherapy for head and neck cancers].
- Source :
-
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique [Cancer Radiother] 2013 Apr; Vol. 17 (2), pp. 130-5. Date of Electronic Publication: 2013 Mar 14. - Publication Year :
- 2013
-
Abstract
- The main indications of brachytherapy for head and neck cancers are limited tumours of the oral cavity, the oropharynx and the nasopharynx. This technique can be exclusive, associated with external radiotherapy or postoperative. This is also a treatment for second localizations in previously irradiated areas. If low-dose rate brachytherapy is the reference, the pulse dose rate brachytherapy by control of the dose rate and optimisation of the dose distribution is the technique to be preferred. High-dose rate brachytherapy is an option. The major prognosis factors of local control and complications are the use of a leaded protection of the mandible, the intersource spacing (1.2-1.4 cm), the volume treated (30 cm(3), i.e. three loops), the safety margin (5 mm), the dose rate (0.5 Gy/h), the total dose (65 Gy in case of exclusive brachytherapy, 25 Gy in case of a combination of external beam irradiation [50 Gy] and brachytherapy in the oropharyngeal carcinomas, 35 Gy in case of a combination of external beam irradiation [40 Gy] and brachytherapy in the oral cavity carcinomas, 60 Gy in case of a second localization in previous irradiated tissues), the delay between external irradiation and brachytherapy (<20 days), the dose per fraction and the treated volume for high-dose rate brachytherapy. Brachytherapy, when possible, is the optimal method of irradiation of head and neck carcinomas with limited volume.<br /> (Copyright © 2013 Société française de radiothérapie oncologique (SFRO). Published by Elsevier SAS. All rights reserved.)
- Subjects :
- Antineoplastic Agents administration & dosage
Antineoplastic Agents therapeutic use
Brachytherapy adverse effects
Combined Modality Therapy
Contraindications
Female
Head and Neck Neoplasms diagnostic imaging
Head and Neck Neoplasms pathology
Head and Neck Neoplasms therapy
Humans
Lymphatic Irradiation
Male
Organs at Risk
Oropharyngeal Neoplasms diagnostic imaging
Oropharyngeal Neoplasms pathology
Oropharyngeal Neoplasms radiotherapy
Oropharyngeal Neoplasms surgery
Prognosis
Radiation Injuries etiology
Radiation Injuries prevention & control
Radiation Protection methods
Radiography
Radiometry
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted
Radiotherapy, Image-Guided
Tumor Burden
Brachytherapy methods
Head and Neck Neoplasms radiotherapy
Subjects
Details
- Language :
- French
- ISSN :
- 1769-6658
- Volume :
- 17
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
- Publication Type :
- Academic Journal
- Accession number :
- 23498590
- Full Text :
- https://doi.org/10.1016/j.canrad.2013.01.007