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A dinucleating ligand which promotes DNA cleavage with one and without a transition metal ion.
- Source :
-
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2013 May 07; Vol. 49 (35), pp. 3655-7. Date of Electronic Publication: 2013 Mar 27. - Publication Year :
- 2013
-
Abstract
- The dinucleating ligand L (1,3-bis[bis(pyridin-2-ylmethyl)amino]propan-2-ol) combined with metal ions efficiently cleaves DNA when M : L is 1 : 1 (M = Co(II) or Fe(III)) at pH 5.5-7.0, with free L being more active at acidic pH than when bound to Zn(II), Cu(II) or Ni(II) at neutral pH.
Details
- Language :
- English
- ISSN :
- 1364-548X
- Volume :
- 49
- Issue :
- 35
- Database :
- MEDLINE
- Journal :
- Chemical communications (Cambridge, England)
- Publication Type :
- Academic Journal
- Accession number :
- 23535906
- Full Text :
- https://doi.org/10.1039/c3cc39067e