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Phylogenetic analysis of the haemagglutinin gene of canine distemper virus strains detected from giant panda and raccoon dogs in China.
- Source :
-
Virology journal [Virol J] 2013 Apr 08; Vol. 10, pp. 109. Date of Electronic Publication: 2013 Apr 08. - Publication Year :
- 2013
-
Abstract
- Background: Canine distemper virus (CDV) infects a variety of carnivores, including wild and domestic Canidae. In this study, we sequenced and phylogenetic analyses of the hemagglutinin (H) genes from eight canine distemper virus (CDV) isolates obtained from seven raccoon dogs (Nyctereutes procyonoides) and a giant panda (Ailuropoda melanoleuca) in China.<br />Results: Phylogenetic analysis of the partial hemagglutinin gene sequences showed close clustering for geographic lineages, clearly distinct from vaccine strains and other wild-type foreign CDV strains, all the CDV strains were characterized as Asia-1 genotype and were highly similar to each other (91.5-99.8% nt and 94.4-99.8% aa). The giant panda and raccoon dogs all were 549Y on the HA protein in this study, irrespective of the host species.<br />Conclusions: These findings enhance our knowledge of the genetic characteristics of Chinese CDV isolates, and may facilitate the development of effective strategies for monitoring and controlling CDV for wild canids and non-canids in China.
- Subjects :
- Animals
China
Cluster Analysis
Distemper Virus, Canine isolation & purification
Genetic Variation
Molecular Sequence Data
RNA, Viral genetics
Sequence Analysis, DNA
Sequence Homology, Amino Acid
Distemper Virus, Canine classification
Distemper Virus, Canine genetics
Hemagglutinins, Viral genetics
Phylogeography
Raccoons virology
Ursidae virology
Subjects
Details
- Language :
- English
- ISSN :
- 1743-422X
- Volume :
- 10
- Database :
- MEDLINE
- Journal :
- Virology journal
- Publication Type :
- Academic Journal
- Accession number :
- 23566727
- Full Text :
- https://doi.org/10.1186/1743-422X-10-109