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Movement disorders in systemic lupus erythematosus and the antiphospholipid syndrome.

Movement disorders in systemic lupus erythematosus and the antiphospholipid syndrome.

Authors :
Baizabal-Carvallo JF
Bonnet C
Jankovic J
Source :
Journal of neural transmission (Vienna, Austria : 1996) [J Neural Transm (Vienna)] 2013 Nov; Vol. 120 (11), pp. 1579-89. Date of Electronic Publication: 2013 Apr 13.
Publication Year :
2013

Abstract

Movement disorders (MDs), particularly chorea, may be the presenting neurological complication of systemic lupus erythematosus (SLE) and the antiphospholipid syndrome (APS), but the association is not often initially recognized. Current evidence suggests an autoimmune mechanism related to antiphospholipid antibodies in these two conditions, although the antigenic target within the central nervous system has not yet been identified. Based on a comprehensive review of the literature, this article summarizes the current knowledge on MDs in SLE and APS. A high index of suspicion is required to make an early diagnosis and initiate appropriate treatment to provide symptomatic relief and to prevent other systemic complications related to the autoimmune process.

Details

Language :
English
ISSN :
1435-1463
Volume :
120
Issue :
11
Database :
MEDLINE
Journal :
Journal of neural transmission (Vienna, Austria : 1996)
Publication Type :
Academic Journal
Accession number :
23580159
Full Text :
https://doi.org/10.1007/s00702-013-1023-z