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Investigation by two-color IR dissociation spectroscopy of Hoogsteen-type binding in a metalated nucleobase pair mimic.

Authors :
Nosenko Y
Menges F
Riehn C
Niedner-Schatteburg G
Source :
Physical chemistry chemical physics : PCCP [Phys Chem Chem Phys] 2013 Jun 07; Vol. 15 (21), pp. 8171-8. Date of Electronic Publication: 2013 Apr 24.
Publication Year :
2013

Abstract

Two Ag(I) ions, deprotonated 1-methyl-thymine (1MT-H)(-) and 1,3-dideaza-adenine (DDA), self-assemble in methanolic solution to a cationic [(Ag)2(1MT-H)(DDA)](+) complex as identified by electrospray ionization mass spectrometry. Assignment of vibrational bands and identification of the silver coordination pattern arise from comparison of one- and two-color Infrared Multiple Photon Dissociation (IRMPD) spectra (1000-4000 cm(-1)) of isolated and trapped complexes to calculated spectra from density functional theory. This approach reveals two structurally and energetically close isomers that resemble a metalated Hoogsteen-like binding motif. The two color IR/IR double resonance scheme proved in particular useful to observe weakly absorbing or weakly fragmenting vibrational modes.

Details

Language :
English
ISSN :
1463-9084
Volume :
15
Issue :
21
Database :
MEDLINE
Journal :
Physical chemistry chemical physics : PCCP
Publication Type :
Academic Journal
Accession number :
23612714
Full Text :
https://doi.org/10.1039/c3cp44283g