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Host and viral factors affecting clinical performance of a rapid diagnostic test for respiratory syncytial virus in hospitalized children.
- Source :
-
The Journal of pediatrics [J Pediatr] 2013 Sep; Vol. 163 (3), pp. 911-3. Date of Electronic Publication: 2013 Apr 30. - Publication Year :
- 2013
-
Abstract
- Respiratory syncytial virus rapid antigen detection tests (RADT) are used widely. RADT exhibited high specificity (97%) and moderate sensitivity (80%) compared with reverse-transcriptase polymerase chain reaction in 720 hospitalized children <3 years old. Older age, prolonged symptoms, and respiratory syncytial virus genotype-B infection were significantly associated with false-negative results of RADT.<br /> (Copyright © 2013 Mosby, Inc. All rights reserved.)
- Subjects :
- Child, Preschool
DNA, Viral analysis
Female
Hospitalization
Humans
Infant
Infant, Newborn
Logistic Models
Male
Multivariate Analysis
Predictive Value of Tests
Prospective Studies
Respiratory Syncytial Virus Infections virology
Respiratory Syncytial Virus, Human genetics
Respiratory Syncytial Virus, Human immunology
Reverse Transcriptase Polymerase Chain Reaction
Sensitivity and Specificity
Antigens, Viral analysis
Chromatography, Affinity
Respiratory Syncytial Virus Infections diagnosis
Respiratory Syncytial Virus, Human isolation & purification
Subjects
Details
- Language :
- English
- ISSN :
- 1097-6833
- Volume :
- 163
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- The Journal of pediatrics
- Publication Type :
- Academic Journal
- Accession number :
- 23639327
- Full Text :
- https://doi.org/10.1016/j.jpeds.2013.03.067