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[Chemical constituents of Nauclea officinalis].
- Source :
-
Yao xue xue bao = Acta pharmaceutica Sinica [Yao Xue Xue Bao] 2013 Feb; Vol. 48 (2), pp. 276-80. - Publication Year :
- 2013
-
Abstract
- In order to study the chemical constituents in the water extract of the stem of Nauclea officinalis, column chromatography over D101 macroporous resin and silica gel and an automatic purification system were used to isolate and purify the chemical constituents from the extract. Nine compounds were obtained. By analysis of the physicochemical properties and spectral data, their structures were identified as naucleamide G (1), 3, 4-dimethoxyphenol-beta-D-apiofuranosyl (1-->6)-beta-D-glucopyranoside (2), kelampayoside A (3), 3alpha, 5alpha-tetrahydrodeoxycordifoline lactam (4), naucleamide A-10-O-beta-D-glucopyranoside (5), pumiloside (6), 3-epi-pumiloside (7), strictosamide (8) and vincosamide (9), separately. Among them, compound 1 is a new compound, compound 2 was found in plants of the genus Nauclea for the first time, and compounds 3 and 4 were isolated from this plant for the first time.
- Subjects :
- Camptothecin analogs & derivatives
Camptothecin chemistry
Camptothecin isolation & purification
Carbolines chemistry
Glucosides chemistry
Indole Alkaloids chemistry
Molecular Structure
Plant Stems chemistry
Vinca Alkaloids chemistry
Vinca Alkaloids isolation & purification
Carbolines isolation & purification
Glucosides isolation & purification
Indole Alkaloids isolation & purification
Plants, Medicinal chemistry
Rubiaceae chemistry
Subjects
Details
- Language :
- Chinese
- ISSN :
- 0513-4870
- Volume :
- 48
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Yao xue xue bao = Acta pharmaceutica Sinica
- Publication Type :
- Academic Journal
- Accession number :
- 23672026