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Dynamic MR imaging of osteoid osteomas: correlation of semiquantitative and quantitative perfusion parameters with patient symptoms and treatment outcome.
- Source :
-
European radiology [Eur Radiol] 2013 Sep; Vol. 23 (9), pp. 2602-11. Date of Electronic Publication: 2013 May 22. - Publication Year :
- 2013
-
Abstract
- Objective: To evaluate the relationship between multiple MR perfusion parameters and symptoms of patients with osteoid osteomas after percutaneous laser therapy.<br />Methods: MR perfusion studies of 20 patients diagnosed with an osteoid osteoma, treated with CT-guided percutaneous laser therapy, were retrospectively evaluated. Multiple perfusion parameters correlated with the treatment outcome and the presence of osteoid osteoma-related symptoms.<br />Results: There were 16 successful treatments, 6 recurrences and a significant difference in the perfusion parameters of these groups (P < 0.0001). Patients with successful treatment demonstrated delayed progressive enhancement or no enhancement (mean time to peak = 182 s, mean delay to the arterial peak = 119.3 s). Patients with treatment failure demonstrated an early and steep enhancement (mean time to peak = 78 s and mean delay to the arterial peak = 24 s). Plasmatic volume and transfer constant values significantly changed after successful treatment (P < 0.008). MR perfusion has a sensitivity and a specificity higher than 90 % in the detection of recurrent osteoid osteomas.<br />Conclusion: The identification of an early and steep enhancement with short time to peak and a short delay between the arterial and nidus peaks on MR perfusion in the postoperative setting is highly indicative of an osteoid osteoma recurrence. Key points • Magnetic resonance perfusion is becoming widely used for several tumours. • MR perfusion measurements correlate well with osteoid osteoma-related symptoms. • MR perfusion has high diagnostic performance for osteoid osteoma recurrence. • MR perfusion can improve the diagnostic confidence of osteoid osteoma recurrence.
- Subjects :
- Adolescent
Adult
Bone Neoplasms pathology
Female
Humans
Image Processing, Computer-Assisted methods
Imaging, Three-Dimensional methods
Laser Therapy methods
Lasers
Male
Osteoma, Osteoid pathology
Perfusion
Recurrence
Sensitivity and Specificity
Software
Tomography, X-Ray Computed methods
Treatment Outcome
Young Adult
Bone Neoplasms diagnosis
Bone Neoplasms therapy
Magnetic Resonance Imaging methods
Osteoma, Osteoid diagnosis
Osteoma, Osteoid therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1432-1084
- Volume :
- 23
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- European radiology
- Publication Type :
- Academic Journal
- Accession number :
- 23695220
- Full Text :
- https://doi.org/10.1007/s00330-013-2867-1