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Association between severe obstructive sleep apnea and incident arterial hypertension in the older people population.
- Source :
-
Sleep medicine [Sleep Med] 2013 Sep; Vol. 14 (9), pp. 838-42. Date of Electronic Publication: 2013 Jul 03. - Publication Year :
- 2013
-
Abstract
- Objectives: The impact of sleep-related breathing disorders on the incidence of arterial hypertension (AHT) in the older adults is not well-established. The aim of our study was to test the link between severe obstructive sleep apnea (OSA) and the occurrence of hypertension in older subjects after 3 years.<br />Methods: 372 normotensive subjects with a mean age of 68.2 years were included in our longitudinal study. All participants had a ventilatory polygraphic recording and an ambulatory blood pressure (BP) monitoring at baseline and after 3 years. Severe OSA was defined by an apnea-hypopnea index (AHI) of ≥ P30 per hour. A new onset of hypertension was defined according to a mean 24-hour value >140mmHg for systolic BP and >85mmHg for diastolic BP or the use of antihypertensive medication.<br />Results: The baseline factors significantly associated with an increased risk for new-onset hypertension were male gender, obesity, diabetes mellitus (DM), dyslipidemia, and OSA. Multiple logistic regression analyses showed that an AHI ≥30 per hour was independently associated with incident hypertension after 3 years (P=.02; odds ratio [OR], 1.8; 95% confidence interval [CI], 1.1-2.8).<br />Conclusions: The presence of severe OSA is associated with new-onset AHT in normotensive elderly (mean age, 68.2 y) subjects.<br /> (Copyright © 2013 Elsevier B.V. All rights reserved.)
- Subjects :
- Age Distribution
Age of Onset
Aged
Antihypertensive Agents therapeutic use
Blood Pressure Monitoring, Ambulatory
Female
Humans
Hypertension diagnosis
Hypertension drug therapy
Incidence
Logistic Models
Longitudinal Studies
Male
Middle Aged
Risk Factors
Severity of Illness Index
Sex Distribution
Hypertension epidemiology
Sleep Apnea, Obstructive epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1878-5506
- Volume :
- 14
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Sleep medicine
- Publication Type :
- Academic Journal
- Accession number :
- 23831239
- Full Text :
- https://doi.org/10.1016/j.sleep.2013.05.002