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Validation of RiskCheck Bladder Cancer ©, version 5.0 for risk-adapted screening of bladder cancer.
- Source :
-
Urologia internationalis [Urol Int] 2013; Vol. 91 (2), pp. 175-81. Date of Electronic Publication: 2013 Jul 16. - Publication Year :
- 2013
-
Abstract
- Introduction: The aim of the study was to assess the strength of the online tool RiskCheck Bladder Cancer©, version 5.0 (RCBC) for early detection of bladder cancer (BC).<br />Materials and Methods: RCBC was evaluated retrospectively based on the data of 241 patients, of which 141 were suffering from BC. Statistical analysis was performed by descriptive statistics, nonparametric group comparison, classification tree analysis and ROC analysis.<br />Results: ROC analysis of the risk classification showed a sensitivity of 71.6%, a specificity of 56.5%, a positive predictive value of 67.8%, a negative predictive value of 52% and an accuracy of 63.5%. BC risk factors ranked by importance are time of smoking (p < 0.0001), gender (within the nonsmoking group: p < 0.009), occupational toxin exposure (within the group <35 years of smoking: p < 0.048) and amount of consumed cigarettes resulting in a 95% association with BC (within the group >35 years of smoking: p < 0.0001).<br />Conclusions: The high predictive power of RCBC for the identification of asymptomatic patients living under risk could be demonstrated.<br /> (© 2013 S. Karger AG, Basel.)
- Subjects :
- Aged
Aged, 80 and over
Algorithms
Female
Humans
Internet
Male
Middle Aged
Neoplasm Staging
Predictive Value of Tests
ROC Curve
Retrospective Studies
Risk Assessment
Risk Factors
Sensitivity and Specificity
Sex Factors
Smoking adverse effects
Software
Diagnosis, Computer-Assisted methods
Early Detection of Cancer methods
Urinary Bladder Neoplasms diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1423-0399
- Volume :
- 91
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Urologia internationalis
- Publication Type :
- Academic Journal
- Accession number :
- 23860006
- Full Text :
- https://doi.org/10.1159/000351036