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Flavan-3-ol-cysteine and acetylcysteine conjugates from edible reagents and the stems of Cynomorium songaricum as potent antioxidants.
- Source :
-
Food chemistry [Food Chem] 2013 Dec 01; Vol. 141 (3), pp. 2691-6. Date of Electronic Publication: 2013 May 14. - Publication Year :
- 2013
-
Abstract
- Flavan-3-ol derivatives, including 3 cysteine conjugates and 3 acetylcysteine conjugates, were prepared using Cynomorium songaricum and edible reagents. The structures were determined, based on NMR and MS spectra. All compounds had stronger radical-scavenging activity than catechin and epicatechin. Moreover, the cysteine conjugates were active against α-glucosidase, whereas catechin and epicatechin were not. Two acetylcysteine flavan-3-ol conjugates, 4β-(L-acetylcysteinyl)-epicatechin 3-O-gallate and 4β-(L-acetylcysteinyl)-epiafzelechin, are novel compounds with better logP values than their cysteine counterparts. These conjugates can be prepared from purified flavan-3-ol polymers or directly from herbal material.<br /> (Copyright © 2013 Elsevier Ltd. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1873-7072
- Volume :
- 141
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Food chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 23871012
- Full Text :
- https://doi.org/10.1016/j.foodchem.2013.05.007