A gold nanocarrier and DNA-metal ligation-based sensing ensemble for fluorescent assay of thiol-containing amino acids and peptides.

Authors :: Li J
Yang S
Zhou W
Liu C
Jia Y
Zheng J
Li Y
Li J
Yang R
Source :: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2013 Sep 18; Vol. 49 (72), pp. 7932-4. Date of Electronic Publication: 2013 Jul 30.
Publication Year :: 2013
Abstract: By engineering a gold nanoparticle and thymine-Hg(2+)-thymine-based hairpin DNA probe, a gold nanocarrier-based strategy for in vitro detection and live-cell imaging of thiol-containing amino acids/peptides was proposed.

Subjects :: Biological Assay
DNA chemistry
Drug Carriers chemistry
Fluorescence
HeLa Cells
Humans
Microscopy, Confocal
Models, Molecular
Cysteine chemistry
DNA Probes chemistry
Gold chemistry
Metal Nanoparticles chemistry
Methionine chemistry
Peptides chemistry

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