Partial genetic characterization of Sedlec virus (Orthobunyavirus, Bunyaviridae).

Authors :: Bakonyi T
Kolodziejek J
Rudolf I
Berčič R
Nowotny N
Hubálek Z
Source :: Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases [Infect Genet Evol] 2013 Oct; Vol. 19, pp. 244-9. Date of Electronic Publication: 2013 Aug 02.
Publication Year :: 2013
Abstract: Sedlec virus (SEDV) was isolated from the blood of a reed warbler (Acrocephalus scirpaceus) in July 1984 in South Moravia, Czech Republic. In this study first genetic data of SEDV are presented which allow an estimate on its phylogenetic and taxonomic positioning within the genus Orthobunyavirus. The phylogenetic analysis of a 369 nt long stretch within the S segment (nucleocapsid protein gene and non-structural S protein gene) indicates genetic relatedness of SEDV to Leanyer virus and Simbu group viruses, while the phylogenetic tree based on 1796nt long sequences of the L segment (RNA-dependent RNA polymerase gene) demonstrates genetic relationship of SEDV to two yet unclassified orthobunyaviruses: I612045 virus (isolated in India in 1961) and Oyo virus (isolated in Nigeria in 1964). Considering the genetic distances and the phylogenetic analyses, SEDV might represent a novel serogroup of the Orthobunyavirus genus.<br /> (Copyright © 2013 Elsevier B.V. All rights reserved.)

Subjects :: Animals
Bunyaviridae Infections virology
Czech Republic
Mice
Orthobunyavirus isolation & purification
Phylogeny
RNA, Viral genetics
Songbirds virology
Virus Cultivation
Orthobunyavirus classification
Orthobunyavirus genetics

Language :: English
ISSN :: 1567-7257
Volume :: 19
Database :: MEDLINE
Journal :: Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
Publication Type :: Academic Journal
Accession number :: 23917024
Full Text :: https://doi.org/10.1016/j.meegid.2013.07.025

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