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A non-nucleoside triphosphate for powering kinesin-microtubule motility with photo-tunable velocity.

Authors :
Perur N
Yahara M
Kamei T
Tamaoki N
Source :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2013 Nov 04; Vol. 49 (85), pp. 9935-7.
Publication Year :
2013

Abstract

Three non-nucleoside triphosphates, one containing an azobenzene moiety, power a kinesin-microtubule system with high motile activity, with an observed maximum velocity of almost half of that obtained with ATP. The cis-trans photoisomerization of the azobenzene unit allows reversible and repeated control over the motile properties of kinesin.

Details

Language :
English
ISSN :
1364-548X
Volume :
49
Issue :
85
Database :
MEDLINE
Journal :
Chemical communications (Cambridge, England)
Publication Type :
Academic Journal
Accession number :
24037324
Full Text :
https://doi.org/10.1039/c3cc45933k