Neurotransmitter receptor and regulatory gene expression in peripheral blood of Brazilian drug-naïve first-episode psychosis patients before and after antipsychotic treatment.

Authors :: Ota VK
Noto C
Gadelha A
Santoro ML
Silva PN
Melaragno MI
Smith Mde A
Cordeiro Q
Bressan RA
Belangero SI
Source :: Psychiatry research [Psychiatry Res] 2013 Dec 30; Vol. 210 (3), pp. 1290-2. Date of Electronic Publication: 2013 Oct 07.
Publication Year :: 2013
Abstract: Little is known about how genes expressed in blood relate to schizophrenia or antipsychotic use. We analyzed gene expression in 10 first-episode psychosis patients and nine controls using PCR Arrays. GABRR2 and CHRNA3 were found to be differentially expressed after risperidone treatment. These genes may be regulated by antipsychotic use.<br /> (© 2013 Elsevier Ireland Ltd. All rights reserved.)

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