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[Combined inflating lung and insufflating calf pulmonary surfactant under general anesthesia in the treatment of postoperative intractable atelectasis].

Authors :
Lu YP
Hu Y
Shi GP
Yao M
Huang B
Zhou XY
Sun JL
DU JL
Xie GH
Fang XM
Source :
Zhonghua yi xue za zhi [Zhonghua Yi Xue Za Zhi] 2013 Jun 18; Vol. 93 (23), pp. 1838-40.
Publication Year :
2013

Abstract

Objective: To explore the efficacy and safety of combined inflating lung and insufflating calf pulmonary surfactant under general anesthesia for treating postoperative intractable atelectasis.<br />Methods: From August 2006 to January 2013, 15 patients with obstinate postoperative atelectasis receiving pressure control lung expansion were enrolled. The bronchial cannula was intubated into the affected side to assist the expanding of the lung, and the calf pulmonary surfactant was insufflated selectively. The chest auscultation and computed tomography (CT) scan was performed at 1 d and 5 d after the procedure respectively, to evaluation the effect. The airway pressure, mean arterial pressure (MAP), heart rate (HR), respiratory rate (RR) and oxygen saturation (SpO2) were recorded before the treatment, during the treatment and after the treatment.Monitoring arterial blood gas before and after treatment.<br />Results: After the expansion of the lung and insufflation of calf pulmonary surfactants, the iconographic scan showed that collapsed alveolar was reinflated in 12 (80.0%) patients at 1 d after the treatment and in 14 patients(93.3%) at 5 d after the procedure.There were not notable vital sign change and complications during the treatment.At after the treatment, 1, 3, 5 and 7 d after the treatment, PaO2 was higher (P < 0.05), and there were not significantly difference in the PaCO2 and pH (P > 0.05) .<br />Conclusion: Combined pressure control lung expansion with selectively insufflating calf pulmonary surfactant under general anesthesia may be an effective therapy for postoperative intractable atelectasis.

Details

Language :
Chinese
ISSN :
0376-2491
Volume :
93
Issue :
23
Database :
MEDLINE
Journal :
Zhonghua yi xue za zhi
Publication Type :
Academic Journal
Accession number :
24124723