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Pathomorphosis of experimental infection in mice, infected by Streptococcus pneumoniae, under the effect of immunotropic drugs.
- Source :
-
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2013 Aug; Vol. 155 (4), pp. 477-83. - Publication Year :
- 2013
-
Abstract
- Pathomorphological changes in the organs of animals intranasally infected with Streptococcus pneumoniae were studied under conditions of immunotropic therapy added to antibiotic therapy. The pathomorphosis in the lungs, spleen, and thymus in animals treated with likopid, tinrostim, and roncoleukin was described. A positive time course of the pathological process in experimental animals in comparison with intact animals and animals receiving no immunotropic drugs was demonstrated.
- Subjects :
- Acetylmuramyl-Alanyl-Isoglutamine pharmacology
Acetylmuramyl-Alanyl-Isoglutamine therapeutic use
Animals
Animals, Outbred Strains
Anti-Bacterial Agents pharmacology
Anti-Bacterial Agents therapeutic use
Aza Compounds pharmacology
Aza Compounds therapeutic use
Community-Acquired Infections drug therapy
Community-Acquired Infections immunology
Drug Evaluation, Preclinical
Drug Therapy, Combination
Fluoroquinolones
Immunologic Factors therapeutic use
Interleukin-2 therapeutic use
Lung drug effects
Lung microbiology
Mice
Moxifloxacin
Pneumonia, Pneumococcal immunology
Quinolines pharmacology
Quinolines therapeutic use
Spleen immunology
Spleen pathology
Streptococcus pneumoniae
Acetylmuramyl-Alanyl-Isoglutamine analogs & derivatives
Dietary Supplements
Immunologic Factors pharmacology
Interleukin-2 pharmacology
Lung pathology
Pneumonia, Pneumococcal drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1573-8221
- Volume :
- 155
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Bulletin of experimental biology and medicine
- Publication Type :
- Academic Journal
- Accession number :
- 24143373
- Full Text :
- https://doi.org/10.1007/s10517-013-2183-4