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Guiding principles of subcutaneous immunotherapy for allergic rhinitis in Japan.

Authors :
Okamoto Y
Ohta N
Okano M
Kamijo A
Gotoh M
Suzuki M
Takeno S
Terada T
Hanazawa T
Horiguchi S
Honda K
Matsune S
Yamada T
Yuta A
Nakayama T
Fujieda S
Source :
Auris, nasus, larynx [Auris Nasus Larynx] 2014 Feb; Vol. 41 (1), pp. 1-5. Date of Electronic Publication: 2013 Nov 01.
Publication Year :
2014

Abstract

Objective: In anticipation of the development of guidelines for antigen-specific subcutaneous immunotherapy (SCIT), we present recommendations that can serve as guiding principles based on a review of the scientific literature.<br />Methods: Clinical questions (CQs) concerning SCIT were prepared. Literature searches for publications between January 1990 and February 2011 were performed in PubMed, the Cochrane Library, and Japana Centra Revuo Medicina Web version 4. Qualified studies were analyzed and the results were evaluated, consolidated, and codified.<br />Results: We present answers for 13 CQs on the indications, methods, effectiveness and mechanisms of SCIT, with evidence-based recommendations.<br />Conclusion: The guiding principles are intended to be applied to children (≤15 years old) and adults (≥16 years old) with allergic rhinitis (AR). These principles can be used by otorhinolaryngologists for diagnosis of AR, evaluation of severity and rhinoscopic findings, performance of antigen challenge tests, and management of systemic anaphylactic reactions associated with SCIT.<br /> (Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.)

Details

Language :
English
ISSN :
1879-1476
Volume :
41
Issue :
1
Database :
MEDLINE
Journal :
Auris, nasus, larynx
Publication Type :
Academic Journal
Accession number :
24183858
Full Text :
https://doi.org/10.1016/j.anl.2013.06.003