Muurolane-type sesquiterpenes from marine sponge Dysidea cinerea.

Authors :: Kiem PV
Minh CV
Nhiem NX
Cuc NT
Quang NV
Tuan Anh HL
Tai BH
Yen PH
Hoai NT
Ho KY
Kim N
Park S
Kim SH
Source :: Magnetic resonance in chemistry : MRC [Magn Reson Chem] 2014 Jan-Feb; Vol. 52 (1-2), pp. 51-6. Date of Electronic Publication: 2013 Nov 14.
Publication Year :: 2014
Abstract: Seven new muurolane-type sesquiterpenes, (4R,5R)-muurol-1(6),10(14)-diene-4,5-diol (1), (4R,5R)-muurol-1(6)-ene-4,5-diol (2), (4R,5R,10R)-10-methoxymuurol-1(6)-ene-4,5-diol (3), (4S)-4-hydroxy-1,10-seco-muurol-5-ene-1,10-dione (4), (4R)-4-hydroxy-1,10-seco-muurol-5-ene-1,10-dione (5), (6S,10S)-6,10-dihydroxy-7,8-seco-2,8-cyclo-muurol-4(5),7(11)-diene-12-oic acid (6), and (6R,10S)-6,10-dihydroxy-7,8-seco-2,8-cyclo-muurol-4(5),7(11)-diene-12-oic acid (7) were isolated from the marine sponge Dysidea cinerea. Their structures were determined by the combination of spectroscopic and chemical methods, including 1D-NMR, 2D-NMR, and CD spectra as well as by comparing the NMR data with those reported in the literature.<br /> (Copyright © 2013 John Wiley & Sons, Ltd.)