Back to Search
Start Over
RPS8--a new informative DNA marker for phylogeny of Babesia and Theileria parasites in China.
- Source :
-
PloS one [PLoS One] 2013 Nov 07; Vol. 8 (11), pp. e79860. Date of Electronic Publication: 2013 Nov 07 (Print Publication: 2013). - Publication Year :
- 2013
-
Abstract
- Piroplasmosis is a serious debilitating and sometimes fatal disease. Phylogenetic relationships within piroplasmida are complex and remain unclear. We compared the intron-exon structure and DNA sequences of the RPS8 gene from Babesia and Theileria spp. isolates in China. Similar to 18S rDNA, the 40S ribosomal protein S8 gene, RPS8, including both coding and non-coding regions is a useful and novel genetic marker for defining species boundaries and for inferring phylogenies because it tends to have little intra-specific variation but considerable inter-specific difference. However, more samples are needed to verify the usefulness of the RPS8 (coding and non-coding regions) gene as a marker for the phylogenetic position and detection of most Babesia and Theileria species, particularly for some closely related species.
- Subjects :
- Animals
Babesia genetics
Base Sequence
Cattle
China
DNA, Protozoan genetics
Exons
Genetic Markers
Humans
Introns
Molecular Sequence Data
Open Reading Frames
Protozoan Proteins genetics
Ribosomal Proteins genetics
Ribosome Subunits, Small, Eukaryotic chemistry
Theileria genetics
Babesia classification
DNA, Protozoan classification
Phylogeny
Protozoan Proteins classification
Ribosomal Proteins classification
Theileria classification
Subjects
Details
- Language :
- English
- ISSN :
- 1932-6203
- Volume :
- 8
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- PloS one
- Publication Type :
- Academic Journal
- Accession number :
- 24244571
- Full Text :
- https://doi.org/10.1371/journal.pone.0079860