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Quantitative psychomotor dysfunction in schizophrenia: a loss of drive, impaired movement execution or both?
- Source :
-
Neuropsychobiology [Neuropsychobiology] 2013; Vol. 68 (4), pp. 221-7. Date of Electronic Publication: 2013 Nov 13. - Publication Year :
- 2013
-
Abstract
- Aims: The aim of the present study was to investigate the predictive value of qualitative psychomotor performance levels and subaspects of the negative syndrome for quantitative motor activity levels in patients with schizophrenia.<br />Methods: Twenty-seven stabilized patients with schizophrenia and 22 age- and sex-matched healthy controls were included in the study. An extensive battery of psychomotor performance tests (Finger Tapping Test, Purdue Pegboard Test, Line Copying Test, Neurological Evaluation Scale, Salpêtrière Retardation Rating Scale), clinical rating scales (Positive and Negative Syndrome Scale) and 24-hour actigraphy were administered to all participants.<br />Results: Correlational analyses showed that motor activity levels were associated with avolition as well as clinically assessed psychomotor slowing. However, in a regression model, only avolition was found to be a significant predictor for motor activity levels in patients with schizophrenia; none of the psychomotor performance tests nor the severity of emotional expressivity deficits contributed to the model.<br />Conclusion: Qualitative and quantitative psychomotor deficits seem to be independent phenomena in stabilized patients with schizophrenia. The diminishing in motor activity in patients with schizophrenia is related to a loss of drive and not to problems in the quality of movement execution.<br /> (© 2013 S. Karger AG, Basel.)
- Subjects :
- Actigraphy
Adult
Antipsychotic Agents adverse effects
Antipsychotic Agents pharmacology
Case-Control Studies
Female
Humans
Male
Neuropsychological Tests
Schizophrenia diagnosis
Schizophrenia drug therapy
Young Adult
Motor Activity drug effects
Psychomotor Performance drug effects
Schizophrenia physiopathology
Schizophrenic Psychology
Volition drug effects
Subjects
Details
- Language :
- English
- ISSN :
- 1423-0224
- Volume :
- 68
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Neuropsychobiology
- Publication Type :
- Academic Journal
- Accession number :
- 24247207
- Full Text :
- https://doi.org/10.1159/000355293