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Confirmation of effectiveness of tocilizumab by ultrasonography and magnetic resonance imaging in biologic agent-naïve early-stage rheumatoid arthritis patients.
- Source :
-
Modern rheumatology [Mod Rheumatol] 2015; Vol. 25 (6), pp. 948-53. Date of Electronic Publication: 2013 Nov 13. - Publication Year :
- 2015
-
Abstract
- Efficacy of tocilizumab in active early-stage RA patients despite methotrexate was evaluated for 12 months. One out of 5 patients was quitted by infusion reaction whereas tocilizumab continued for 12 months in the remaining 4 patients. Power Doppler articular synovitis was reduced in every patient and disappeared in 2 patients. Marked MRI osteitis, found in 1 patient, had disappeared at 12 months. Present results confirm the efficacy of tocilizumab by ultrasonography and MRI.
- Subjects :
- Adult
Arthritis, Rheumatoid diagnostic imaging
Female
Humans
Magnetic Resonance Imaging methods
Male
Methotrexate therapeutic use
Middle Aged
Synovitis diagnostic imaging
Treatment Outcome
Ultrasonography
Antibodies, Monoclonal, Humanized therapeutic use
Antirheumatic Agents therapeutic use
Arthritis, Rheumatoid drug therapy
Synovitis drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1439-7609
- Volume :
- 25
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Modern rheumatology
- Publication Type :
- Academic Journal
- Accession number :
- 24252054
- Full Text :
- https://doi.org/10.3109/14397595.2013.844394