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Clinical outcome after crush versus culotte stenting of coronary artery bifurcation lesions: the Nordic Stent Technique Study 36-month follow-up results.
- Source :
-
JACC. Cardiovascular interventions [JACC Cardiovasc Interv] 2013 Nov; Vol. 6 (11), pp. 1160-5. - Publication Year :
- 2013
-
Abstract
- Objectives: The aim of the study was to compare long-term follow-up results of crush versus culotte stent techniques in coronary bifurcation lesions.<br />Background: The randomized Nordic Stent Technique Study showed similar 6-month clinical and 8-month angiographic results with the crush and culotte stent techniques of de novo coronary artery bifurcation lesions using sirolimus-eluting stents. Here, we report the 36-month efficacy and safety of the Nordic Stent Technique Study.<br />Methods: A total of 424 patients with a bifurcation lesion were randomized to stenting of both main vessel and side branch with the crush or the culotte technique and followed for 36 months. Major adverse cardiac events-the composite of cardiac death, myocardial infarction, stent thrombosis, or target vessel revascularization-were the primary endpoint.<br />Results: Follow-up was complete for all patients. At 36 months, the rates of the primary endpoint were 20.6% versus 16.7% (p = 0.32), index lesion restenosis 11.5% versus 6.5% (p = 0.09), and definite stent thrombosis 1.4% versus 4.7% (p = 0.09) in the crush and the culotte groups, respectively.<br />Conclusions: At 36-month follow-up, the clinical outcomes were similar for patients with coronary bifurcation lesions treated with the culotte or the crush stent technique. (Nordic Bifurcation Study. How to Use Drug Eluting Stents [DES] in Bifurcation Lesions? NCT00376571).<br /> (Copyright © 2013 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.)
- Subjects :
- Aged
Coronary Angiography
Coronary Artery Disease diagnosis
Coronary Artery Disease mortality
Coronary Restenosis etiology
Coronary Thrombosis etiology
Female
Finland
Humans
Latvia
Male
Middle Aged
Percutaneous Coronary Intervention adverse effects
Percutaneous Coronary Intervention mortality
Prosthesis Design
Risk Factors
Scandinavian and Nordic Countries
Time Factors
Treatment Outcome
Cardiovascular Agents administration & dosage
Coronary Artery Disease therapy
Drug-Eluting Stents
Percutaneous Coronary Intervention instrumentation
Percutaneous Coronary Intervention methods
Sirolimus administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 1876-7605
- Volume :
- 6
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- JACC. Cardiovascular interventions
- Publication Type :
- Academic Journal
- Accession number :
- 24262616
- Full Text :
- https://doi.org/10.1016/j.jcin.2013.06.009