Back to Search
Start Over
MiR-210: A potential therapeutic target against radiation-induced enteropathy.
- Source :
-
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology [Radiother Oncol] 2014 May; Vol. 111 (2), pp. 219-21. Date of Electronic Publication: 2013 Nov 26. - Publication Year :
- 2014
-
Abstract
- A previously undescribed and robust miR210 overexpression is shown in intestinal samples obtained from patients with radiation enteropathy and fibrotic cultured cells. In addition, miR-210 overexpression is repressed by antifibrotic treatment combining pentoxifylline and α-tocopherol.<br /> (Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.)
- Subjects :
- Antioxidants therapeutic use
Cells, Cultured drug effects
Cells, Cultured metabolism
Drug Therapy, Combination
Fibrosis drug therapy
Fibrosis metabolism
Humans
Hypoxia metabolism
Intestinal Diseases metabolism
MicroRNAs antagonists & inhibitors
Molecular Targeted Therapy methods
Myocytes, Smooth Muscle drug effects
Myocytes, Smooth Muscle metabolism
RNA metabolism
RNA, Mitochondrial
Radiation Injuries metabolism
Radiotherapy adverse effects
alpha-Tocopherol therapeutic use
Intestinal Diseases drug therapy
MicroRNAs metabolism
Pentoxifylline therapeutic use
Platelet Aggregation Inhibitors therapeutic use
Radiation Injuries drug therapy
Radiation-Protective Agents therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 1879-0887
- Volume :
- 111
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
- Publication Type :
- Academic Journal
- Accession number :
- 24290534
- Full Text :
- https://doi.org/10.1016/j.radonc.2013.10.030