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Neurotrophic effects of beta endorphin C-terminal tetrapeptide (MPF)
- Source :
-
Neuropeptides [Neuropeptides] 1986 Jul; Vol. 8 (1), pp. 45-9. - Publication Year :
- 1986
-
Abstract
- The ability of newts and other urolele amphibians to regenerate an accidentally-removed or amputated limb is lost after hypophysectomy, but restored following intraperitoneal injection of beta endorphin, or the C-terminal tetrapeptide sequence of human beta endorphin, Lys-Lys-Gly-Glu (= MPF). The closely related tetrapeptide, Lys-Lys-Gly-Gln (the C-terminal sequence of pig, sheep, and camel beta endorphin), the dipeptide Gly-Glu, the enkephalins, and other N-terminal sequences of beta endorphin (eg gamma endorphin) do not elicit the effect.
Details
- Language :
- English
- ISSN :
- 0143-4179
- Volume :
- 8
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Neuropeptides
- Publication Type :
- Academic Journal
- Accession number :
- 2429228
- Full Text :
- https://doi.org/10.1016/0143-4179(86)90063-6